Trey Lance couldn’t rally the 49ers in the fourth quarter after their defense went into a second-half freefall against the Chicago Bears.
Chicago quarterback Justin Fields played a massive factor, too. His scrambling drove the 49ers’ defense mad — and induced them into untimely penalties — but he also threw two touchdown passes to avenge last season’s 33-22 loss.
Deebo Samuel scored the 49ers first — their only — touchdown on a 6-yard, second-quarter run.
But the offense did not have tight end George Kittle (inactive; groin) and it lost starting running back Elijah Mitchell to a knee injury, which he apparently sustained after blocking on Samuel’s touchdown run.
The Bears celebrated with belly slides into the end zone, reminiscent of the 49ers’ rain-soaked win at Washington in 2019.
There would be no joy in the 49ers’ locker room like in their past two visits. There would be an ugly loss, the fourth to start a season in coach Kyle Shanahan’s six seasons.
Bay Area News Group’s Cam Inman contributed to this report.
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